SNFGE SNFGE
 
Thématique :
- MICI
Originalité :
Intermédiaire
Solidité :
Très solide
Doit faire évoluer notre pratique :
Dans certains cas
 
 
Nom du veilleur :
Docteur Stéphane NAHON
Coup de coeur :
 
 
Clinical Gastroenterology and Hepatology
  2017/06  
 
  2017 Jun;15(6):857-863  
  doi: 10.1016/j.cgh.2016.10.039.  
 
  Incidence and Prevalence of Crohn’s Disease and Ulcerative Colitis in Olmsted County, Minnesota From 1970 Through 2010  
 
  Shivashankar R, Tremaine WJ, Harmsen WS, Loftus EV Jr  
  https://www.ncbi.nlm.nih.gov/pubmed/27856364  
 
 

Abstract

BACKGROUND & AIMS:

The incidence and prevalence of inflammatory bowel diseases (IBD) continue to increase worldwide. We sought to update incidence rates of Crohn's disease (CD) and ulcerative colitis (UC) in a well-defined United States population, calculating values for Olmsted County, Minnesota through 2010. We also calculated prevalence values.

METHODS:

The resources of the Rochester Epidemiology Project were used to identify county residents who were diagnosed with IBD (CD or UC), based on previously set criteria. Those with new diagnoses of CD or UC between 1970 and 2010 were identified as incidence cases, and those meeting diagnostic criteria on January 1, 2011, were identified as prevalence cases. Incidence rates were estimated (adjusted for age and sex to the US white population in 2010). Trends in incidence based on age at diagnosis, sex, and year of diagnosis were evaluated by Poisson regression.

RESULTS:

The incidence cohort included 410 patients with CD (51% female) and 483 individuals with UC (56% male). Median age of diagnosis was 29.5 years for persons with CD (range, 4-93 years) and 34.9 years for UC (range, 1-91 years). From 2000 through 2010, the adjusted annual incidence rate for CD was 10.7 cases per 100,000 person-years (95% confidence interval [CI], 9.1-12.3 person-years) and for UC was 12.2 per 100,000 (95% CI, 10.5-14.0 person-years). On January 1, 2011, there were 380 residents with CD, with an adjusted prevalence of 246.7 cases per 100,000 persons (95% CI, 221.7-271.8 cases per 100,000 persons), and 435 residents with UC, with an adjusted prevalence of 286.3 (95% CI, 259.1-313.5 cases per 100,000 persons). Male sex was significantly associated with a higher incidence rate of UC, and younger age was significantly associated with a higher incidence rate of CD.

CONCLUSIONS:

Estimated incidence rates for UC and CD in Olmsted County are among the highest in the United States. Extrapolating the adjusted prevalence to the most recent US Census, there could be approximately 1.6 million persons in the United States with IBD.

 

  
Question posée
 
Quelles sont les incidence et prévalence de la maladie de Crohn et de la RCH dans le comté d’Olmsted (Mayo Clinic) et l’évolution dans le temps ?
  
Question posée
 
L’incidence de la maladie de Crohn est de 10,7 pour 100 000 habitants et de 12,2/100 000 h pour la RCH (enregistrement des cas depuis 1970 ; calcul effectué entre 2000-2010). Une extrapolation à l’ensemble de la population américaine montre une prévalence de 1,6 millions de MICI en 2011.
  
Commentaires

Cette étude en population montre une prévalence élevée des MICI aux Etats-Unis avec une incidence accrue de la RCH/maladie de Crohn. Parallèlement, on note une augmentation des cas de MICI entre les années 70 et 2010.
 
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