Thématique :
- Endoscopie/Imagerie
Originalité :
Solidité :
Doit faire évoluer notre pratique :
Nom du veilleur :
Docteur Edouard Chabrun
Coup de coeur :
  2016 Jan;48(1):62-70  
  doi: 10.1055/s-0034-1392514. Epub 2015 Jul 28.  
  Risk of stricture after endoscopic submucosal dissection for large rectal neoplasms.  
  Ohara Y, Toyonaga T, Tanaka S, Ishida T, Hoshi N, Yoshizaki T, Kawara F, Lui KL, Tepmalai K, Damrongmanee A, Nagata M, Morita Y, Umegaki E, Azuma T  


Improvements in the endoscopic submucosal dissection (ESD) technique have made circumferential ESD in the rectum possible. However, little is known about the clinical course after extensive ESD in the rectum. The aim of this study was to determine the stricture risk in the rectum after total or subtotal circumferential ESD.


A total of 69 patients with 69 rectal tumors that required ≥ 75 % circumferential resection were identified at Kobe University Hospital and an affiliated hospital between April 2005 and May 2014. Among the patients, 61 were available for evaluation of stricture development, either by follow-up colonoscopy or by surgical specimens. The rate and possible risk factors of post-ESD strictures were investigated.


Post-ESD rectal strictures developed in 12 patients (19.7 %). Patients who underwent total circumferential ESD developed a stricture (5/7, 71.4 %) more frequently than those with subtotal (≥ 90 %) ESD (7/16, 43.8 %). Patients undergoing an ESD procedure that involved < 90 % of the circumference did not develop strictures. The strictures were membranous or < 10 mm long in all cases. Of the patients with stricture, 11 received endoscopic balloon dilation and one received bougie with short-caliber-tip transparent hood; all strictures improved following dilation therapy. Statistical analysis revealed that ≥ 90 % circumferential resection was an independent risk factor for stricture, whereas morphology and size were not.


Patients who underwent total or subtotal circumferential ESD of a rectal tumor had a high risk of stricture formation. Dilation helped to alleviate the stenosis.Study registered at University Hospital Medical Information Network (UMIN 000016559).

Question posée
Quels sont les facteurs de risque de sténose rectale après dissection sous-muqueuse (ESD) de large lésion ?
Question posée
Les sténoses rectales post-ESD sont rares et favorisées par la résection de lésion occupant ≥ 90% de la circonférence rectale.